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Psilocybin is a chemical compound derived from specific varieties of hallucinogenic mushrooms. Psilocybin falls under the category of indole-alkylamines, specifically tryptamines, and shares a structural resemblance with lysergic acid diethylamide (LSD).

People seek this compound due to its hallucinogenic and euphoric effects. The psychedelic effects of psilocybin stem from its interaction with serotonin (5-HT) receptors in the central nervous system.

Psilocybin interacts with the brain’s prefrontal cortex, which governs abstract thinking, mood regulation, and perception.

Research and anecdotal evidence suggest many users report sensations of euphoria, transcendence, or mystical encounters.

Colours and sounds may intensify, which alters the perception of surroundings and fosters a sense of openness, connection to the world, and enhanced introspection.

Microdosing means consuming minimal, sub-perceptible doses of psychedelics at regular intervals. A usual microdose ranges from 0.1 to 0.5 grams, taken weekly with a few days skipped. It does not impair normal functioning but offers benefits when taken in this manner.

• Mood enhancement or amplification of mood
• Increased energy
• Relaxation and body awareness
• Increased ability to meditate
• Increase in creativity
• Enhanced appreciation of the arts
• Increased productivity and ability to focus
• Stabilized emotions
• Stress reduction

Psilocybin interacts with serotonin receptors, so you must avoid using medications that alter the serotonin system, like SSRI antidepressants such as Prozac.

Psilocybin should not be mixed with Tramadol because it can lead to Serotonin Syndrome. Psilocybin combined with amphetamines or other recreational drugs is also bad news.

Psilocybin induces effects akin to those of other hallucinogens like mescaline from peyote or LSD. These effects encompass visual and auditory hallucinations and a diminished ability to differentiate between fantasy and reality.

Hallucinogens that impact serotonin can influence various bodily functions such as mood, sensory perception, sleep, appetite, body temperature, sexual behaviour, and muscle control.

Other effects:

• Intensify feelings and sensory experiences
• Alter the perception of time
• Elevate physiological parameters like blood pressure and breathing rate
• Diminish appetite
• Disrupt sleep
• Create synesthetic experiences
• Provoke spiritual sensations
• Foster relaxation or detachment from oneself and surrounding

• Consider fasting for 4-12 hours to minimize the likelihood of nausea and enhance the potency of the experience.
• Gradually drink water over several hours to prevent headaches, which can result from the emotional toll of the experience.
• Setting intentions before the trip can channel energy in the desired direction. Writing them down in a journal or displaying them serves as a guiding anchor throughout the experience.
• Create a conducive setting by tidying up your surroundings and adjusting the lighting for a soothing ambiance.
• Prepare a kit with essentials like earplugs, first aid supplies, snacks, and layers of clothing to manage temperature fluctuations.
• Allocate a day free of obligations after the journey for integration and reflection.

A magic mushroom trip spans roughly 4 to 6 hours, with its peak hitting around 2 to 3 hours post-ingestion. During the first hour, you might experience mild anxiety. It’s necessary not to take more during this phase, as it could lead to unintended consequences.

As the trip peaks, you undergo the most intense sensory and psychological alterations. This moment calls for relaxation and embracing any feelings or perceptions that arise.

1. Chew and Swallow: Simply chew mushrooms thoroughly or use a grinder to minimize taste.
2. Magic Mushroom Tea: Steep dried mushrooms to make tea, control dosage and mask flavour with lemon, ginger, or honey.
3. Shroom Smoothie: Blend mushrooms with fruits to hide the flavour.
4. Magic Mushroom Capsules: Encapsulate powdered mushrooms for convenient dosing.
5. Lemon Tek: Soak ground mushrooms in lemon or lime juice to hasten onset.

In 2021, the Journal of Psychopharmacology published an analysis exploring this question. Researchers examined data from ten studies involving 288 participants who received psilocybin at doses ranging from 20 to 30 mg for every 70 kg of their weight.

The findings revealed that across all three groups, there was no clear correlation between body weight and the effects of psilocybin. This suggests that a fixed dose is practical, cost-effective, and just as effective as adjusting the dose based on weight.

Rather than fixating on weight-based adjustments, start with conservative doses and gradually increase as you become more acquainted with the psychedelic experience.