Experts Use New Ways to Discover Psilocybe Mexicana Potency and Other Strains for Safer Medical Use

Psilocybe mexicana potency was farfetched until it wasn’t—the psychedelic research community has dramatically changed all due to psilocybin. Discoveries of its therapeutic possibility happen left and right, slowly opening the public’s eyes to medicinal acceptance. Experts see this burgeoning landscape as promising, so they always try ways to measure its dosage, making sure it’s safe for medical use.

Key Takeaways

1. Researchers utilized liquid chromatography paired with tandem mass spectrometry to determine shroom potencies, referring to it as new and innovative.
2. Psilocybe Mexicana, along with other mushrooms, is being explored through clinical studies to test robustness for therapeutic usage.
3. Genetic diversity in magic mushrooms is necessary to create an accurate dosage chart.

Psychedelic Mushrooms, Not a Big Deal Then Until Research Happened 

Previously, you could only count on your fingers how many conditions Psilocybe Cubensis would greatly help with. As of today, psilocybin is making, if not waves, tidal waves of development and progress in terms of its hidden medical applications.

Experts are exploring the open gallery Psilocybe Mexicana and other potent strains as the key ingredient for clinical trials and numerous research efforts. Regardless of in vivo or in vitro subjects, this strain is efficient in delivering the most genuine, authentic effects and benefits of the fungal species.

Market-penetrating Psychedelics

Hidden before, present today—progression and major findings are continuously piquing the recreational interest of the public, especially those patients with therapeutic needs. Conventional treatments for mental health conditions frequently fail, which leaves people seeking a much more reliable alternative.

This is when magic shrooms enter. 

Patients with underlying mental health problems turn to psilocybin, as it was found to be promising in treating depression, alcohol abuse, anxiety, compulsions, tics, chronic pains, etc. 

As of writing, clinicians are finding new ways and alternatives to efficiently and meticulously measure the “just the right” dosage for proper and safe patient administration. Relatively, a group of researchers from the University of Texas (UT) have materialized a model in which psilocybin and psilocin concentrations extracted from shrooms can be clinically determined. 

Why Mexicana Stands Out

Golden Teachers, Blue Meanies, and B-Plus have been overly used in studies, and for researchers to expand the coverage of safe magic mushroom usage, they must branch out into other species. 

Mexicana happens to be a research favourite, not because it’s one of the oldest, but because it has a low-kicking potency that is very likely to meet the medical drug standards.

Compared to high-punching species, this Mexican cultivar is considered an ease to mild shrooms. Despite its lower strength, it can still induce the same impact as other mainstream cubes. Since microdosing is gaining popularity among patients, this is a top-notch choice.

It emulates similar cultivars due to its consistency in psilocybin and psilocin levels. If you’re asking, “If it matches similar strains, then why not choose those instead of Mexicans? Well, their historical and anthropological appeal can answer this.

Recounting A very “Mexican” History

It’s been well established that during ancient times, with nature as a habitat, psilocybe mexicana grew in moss. Indigenous people hailed psilocybin mushrooms for their many occasion applications, frequently associated with the mystical or supernatural. 

But let’s focus on Mexican shrooms. The first recorded account of shroom use was over 2000 years ago, mainly used by the natives of North and Central America. To the then civilization of ethnic groups called the Aztecs, this shroom was described to be the “food for the Gods,” or what they call “teonanácatl” in their native language.

If Aztecs visited us today, they could attest to how perspective-changing, emotionally-bending, and mentally-stabling Mexicana are—even though, by literal means, they couldn’t understand these terminologies. 

Regardless of its many curation and cultivation processes, it managed to preserve its natural psilocybin concentrations—speaking highly of its authenticity. This genuineness is a conventionally acknowledged criterion that many researchers and psychedelic research institutions would pay just to get their hands on. 

Innovative Methods in Psilocybin Content and Potency Testing

A team of ten researchers from the University of Texas from Arlington and other research institutions created a new model of potency testing for shroom’s psychoactive compounds. This new measurement pattern is a concoction of liquid chromatography paired with tandem mass spectrometry.

Two Innovative Ways:

1. Liquid chromatography is the method of separating and examining mixtures of chemicals, in this context, in shrooms’ active chemicals. It passes a liquid sample through a column packed with a solid material (the stationary phase). Different chemicals in the sample may interact with the immobile and mobile phases differently, causing them to separate as they move through the column at different rates.
2. Spectrometry, in general, is the study of how matter interacts with electromagnetic radiation in many different wavelengths. It identifies and quantifies the substance through specific wavelengths of light absorbed and scattered by molecules, determining the chemical’s electronic, vibrational, and rotational states.

They used five magic mushroom strains for this technique. The researchers found that the average total of psilocybin and psilocin levels for five shrooms was 1.36 to 0.879. This concentration outperforms many cultivars, like Bull Run or Cambodian. Of course, they won’t close the study without any assurance that it’s accurate. To do so, they compared it to other separate labs.

They saw similar results between the two laboratories, further evidencing their sequence of tests to determine whether the shroom’s strength was accurate. 

If affirmed by experts, this can add a new layer of techniques to the known psychedelic strength test methods, adding up as a safety net to eliminate unsafe dosage measurements.

Expanding Research to Other Species

Extending research on different species is productive. It can help researchers understand different strains’ capacity to induce health benefits and provide data as the basis for the effects of lower-potency mushrooms.

Further, it may help experts make people understand how varying dosages influence the psychedelic experience. Researchers can identify how different levels of active compounds affect therapeutic outcomes by comparing Mexicans with more potent strains like Psilocybe Cubensis. 

For instance, the Blue Meanies produce more intense hallucinogenic effects, which can be helpful in treating conditions like depression at higher doses. In contrast, the former may be better suited for microdosing or more subtle uses like mood upliftment or focus boost.

Genetic Diversity Means Safer Treatments

Many don’t know that different cultivars or kinds are bound with unique genetic profiles and vary in strength, chemical composition, and effects. Understanding this diversity allows clinicians to select the most suitable type for specific medical applications and curate doses specific to people’s needs while reducing risks and maximizing benefits. 

Let’s take the example of Psilocybe Semilanceata (Liberty Caps) or Psilocybe cyanescens, which have unique alkaloid profiles that might effectively treat anxiety. In contrast, other artificially cultivated mushrooms may be more suited to substance abuse or compulsions. The diversity enables the development of personalized treatments with enhanced safety and efficacy.

We can learn here that hallucinogenic mushrooms’ genetic diversity, with new ways of strength assessment and identification, is necessary for developing safer medical treatments.

Safer Medical Use Outcomes

Let’s take this time to imagine the outcomes of safer dosages. 

• Fewer incidents of overdosing: Through accurate doses, users won’t have to worry about the instances of getting overdosed. This would also mean that product labels must be more accurate to avoid confusing consumers.
• Higher predictability rates: People can predict the effects or impacts they may encounter during the trips with more accurate dosing. This can lessen the overwhelming sensations and anxious mentality, resulting in patient complacency.
• Standardized ratio: One way or another, dosing accuracy can foster a standardized measurement so people can quickly look at charts for possible impacts.

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Frequently Asked Questions

Is Mexico Psilocybe Mexicana similar to the Big Mexicans?

No. Big Mexicans is a strain categorized under Psilocybe Cubensis. They’re two different species, so don’t be confused. Big Mexicans have more compound isolation, from 0.5% to 1%, making it much more potent than the former. Just remember that they are distinct when it comes to appearance. The former’s cap tends to be bell-shaped, and the latter tends to be conical.

What’s the peak concentration of Mexican shrooms?

They ultimately peak at 0.25%, both in psilocybin and psilocin. These isolation levels are considered low-kicking, matching Golden Teacher’s strength. However, they can still induce stimulating psychedelic trips, enough to produce health benefits.

What dosing is considered medically safe?

The frequent prescription will range from 1 to 2 grams. However, this may depend on consumption methods, metabolism, and the strain’s overall potency. Others take sub-thresholds ranging from 0.05 (50mg)  to 0.025 grams (250mg) for the sake of decreasing the hallucinogenic impacts.