First-Ever Approved Psychedelic Mushroom By Health Canada

Health Canada’s recent approval of a psychedelic mushroom for cluster headaches marks a groundbreaking milestone in the field of medicinal psychedelics. This mushroom, containing one of the many controlled substances, is under the Food and Drug Regulations and Substances Act, which means access can only be through Health Canada. With the help of clinical trials, many Canadians from British Columbia to other provinces can now buy psychedelics Canada to manage cluster headaches.

Overview of Cluster Headaches

A cluster headache is a pain on one side of your head that lasts 15 minutes to three hours. It can occur at the same time each day and up to eight times per day. These clusters occur in six-week to three-month stints, one to two times a year, or at a change of seasons.

The pain is comparable to being shot in the eye four to five times a day. It is not only debilitating but unbearable.

Risk Factors

• Sex. More men have cluster headaches than women.
• Age. Most people who develop cluster headaches are between the ages of 20 and 50, but the condition can start at any age.
• Smoking. People who get cluster headaches are smokers. Quitting smoking doesn’t stop the headaches.
• Substance use. Alcohol may increase the risk of an attack.
• Family history. Genetics might increase the risk of cluster headaches.

Health Canada’s Approval Process: A Milestone of Psilocybin Usage 

Lance’s win comes two weeks after Federal Court Judge Simon Fothergill ruled that Health Canada had entirely disregarded the arguments asserting Lance’s Charter right to medical-grade psilocybin.

Lance, a former Alberta land surveyor in his 50s, suffered severely from cluster headaches. Conventional therapies had failed to provide relief, so he explored Psilocybe cubensis’ active compound under his neurologist’s guidance. He discovered that small, non-hallucinogenic doses alleviated his symptoms.

Due to its limited access, Lance found it difficult to search for a reputable source. His case involved challenges under Canada’s Charter of Rights and Freedoms, which focused mainly on his rights to life, liberty, and security under Section 7 of the Charter.

Court’s Verdict

Lance’s lawyer, Nicholas Pope, successfully argued that denying Lance access endangered his life and violated his Charter rights. The Federal Court intervened to overturn Health Canada’s initial refusals and grant Lance access to a psilocybin extract.

This approval marked a significant milestone. It was the first time Health Canada had granted access to P. cubensis’ active compound for treating cluster headaches. It set a precedent for future cases seeking access to therapeutic benefits.

It underscored the evolving understanding and recognition of psychedelics’ therapeutic potential, particularly in treating conditions where conventional treatments had proven ineffective.

Research Involving Psychoactive Substances For Cluster Headaches

Cluster headache patients often experience suicidal thoughts, and half have exhibited self-injurious behaviour during attacks. There is no cure, so treatment aims to reduce pain, shorten the period, and prevent new attacks. 

The active substance in magic mushrooms (Psilocybe cubensis) provides more effective and long-lasting relief compared to conventional treatments.

Yale University

In a randomized, double-blind clinical trial, the research team confirmed that the active compound in Psilocybe cubensis can relieve cluster headache pain and reduce the frequency of attacks.

In the three weeks after starting the treatment, cluster headache attacks decreased from an average of 18.4 attacks per week to 9.8. A reduction of approximately 50% occurred in all participants, regardless of their response in the first round. Most participants tolerated the active compound without unexpected or severe adverse events like multi-system organ failure.

Other Relevant Descriptive Studies 

A study from the Journal of Neuropharmacology 2022 explored the medical use of psychoactive substances for pain. The researcher looked into multiple studies, from surveys to case reports.

Study Design	Dosing Regimen	Preventative Effects	Adverse Effect
Case report	Magic mushroom, 1g every 1 or 2 months	2-6 weeks pain-free	None
Survey	LSD, psilocybin (variable regiments)	Effectiveness: Psilocybin (52%) and LSD (88%)	None
Survey	Psilocybin, LSD, DMT (variable regiments, given every few weeks to every year)	Effectiveness: LSD (78%), Psilocybin (71%), and DMT (44%)	Wooziness, abdominal cramping (in an IBS patient)
Survey	Psilocybin, LSD, LSA (variable regiments of sub-psychedelic doses, 1-3 times per year	Approximately 75% of participants who used at least 1 of the drugs had a full or partial response	None
Survey	Psilocybin, LSD (regimen not specified)	Reduction in attach frequency: Psilocybin (56%) and LSD (60%)	None

How do Psychedelics Work in Cluster Headaches?

Psychedelics appear to work in cluster headaches through several mechanisms, although the exact pathways are not fully understood. Some key aspects may include:

• Serotonin Receptor Activation: Exert effects by binding to the brain’s serotonin receptors, particularly the 5-HT2A receptors. This interaction modulates serotonin signalling, which affects pain perception, mood regulation, and vascular function.
• Neuroplasticity and Connectivity: Help reset dysfunctional pain processing pathways associated with cluster headaches, potentially reducing the frequency and intensity of headache attacks.
• Altered Brain Activity: Studies using functional imaging techniques have demonstrated that psychedelics induce changes in brain activity patterns. These alterations may affect how the brain processes sensory information, like pain signals.
• Anti-Inflammatory Effects: Clinical research suggests that psychedelics may have anti-inflammatory properties, which could contribute to alleviating pain.
• Psychological Factors: Induce profound changes in consciousness, mood, and perception. These altered states of consciousness may lead to psychological insights or experiences that could influence one’s perception of pain or stress.

Administration and Preparation When Consuming Psilocybe Cubensis

Unlike ingesting medication, P. cubensis fungi require understanding and proper preparation. Regardless of the dosage, you must consider these steps to reap this substance’s benefits.

• Education and Research: Begin by educating yourself thoroughly about the substance and its effects. 
• Setting: Plan the administration in a comfortable and safe environment. Choose a calm and familiar place where you feel relaxed and secure, ideally with a trusted person to provide support.
• Dosage Considerations: Start with a low dose, a microdose, to gauge its effects on your condition. Adjust the dosage based on your experience and any guidance from your healthcare provider.
• Mindset: Prepare mentally and emotionally for the experience. Set intentions for your session and focus on how you hope it may alleviate your cluster headache or improve your overall well-being.
• Integration: After your session, reflect on the experience. Journal your thoughts and feelings and note any changes. Discuss these with your healthcare provider to evaluate the next steps.

Access Psilocybe Cubensis from a Reliable Source

You no longer have to deal with shady dealers. Shrooms are now available through reputable online dispensaries that can ship orders anywhere in Canada. Explore these selections for pain relief.

Product	Content or Potency	Price	Form
Blue Pulaski	Average	$20/ 3.5grams	Dried Shroom
White Burma	Above Average	$20/ 3.5grams	Dried Shroom
Koh Samui	Average	$20/ 3.5grams	Dried Shroom
Bright Future – Daily Dose	3g	$105	Tincture
Kind Stranger – Microdose Capsules – Brighten	250mg/ capsule	$94 /15 capsules	Capsules
Osmosis – Immune Support	100mg/ capsule	$90/ bottle (30 pieces)	Capsules

Manage Pain, Mental Illness, and More with Psilocybe Mushrooms

Zoomies Canada is a trusted online magic and medicinal mushroom dispensary specializing in high-quality psychedelics. Our products have the potential to alleviate the intense pain and frequency associated with cluster headaches. 

We know the challenges of managing pain and are committed to providing supportive products tailored to your needs. Even your mental health conditions, like treatment-resistant depression, can benefit from our product selection.

Frequently Asked Questions

Can tripping with Psilocybe cubensis also help in managing headaches?

Yes. Any dosage can relieve pain because the mechanism of action remains the same. Higher doses have the added benefit of inducing spiritual effects, which some studies show can lead to positive personality changes.

Do LSD and P. cubensis fungi differ in treating cluster headaches?

Both controlled drugs affect the serotonin system but can also interact with other pathways that differ between them. While both can induce pain relief at varying dosages, they have distinct effects and durations.

Personal preference and past experiences with each substance may influence your decision. LSD is much more potent, which makes it easier to ingest too much and experience unexpected perceptual effects.

What is the standard dosage regimen to treat cluster headaches?

• Initial Microdosing Phase: Begin with a microdose of magic mushroom, around 0.1 grams (100 mg) to 0.5 grams (500 mg), taken every third day. 
• Therapeutic Dosing: If microdosing proves effective and well-tolerated, some protocols suggest occasional therapeutic doses, from 1 to 2 grams of dried mushrooms, spaced out by several weeks. You can add more if you want stronger visual changes in perception.

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